Japanese scientist Osumi Josinori received the 2016 Nobel Prize in Medical and Physiology for his achievements in the field of cell research.
Osumi Josinori’s results led to the ongoing revolution in autophagy research, as he discovered in yeast the genes whose products are needed for the most important pathway of autophagic degradation. The essence of autophagy is the dynamic balance of cellular recovery and degradation. It is a self-renewing process for the breakdown and recycling of cells' own materials and cellular organs, so the reduced function of autophagy contributes to the development of aging, cancer and neuronal cell death, such as Alzheimer's disease, Parkinson's disease, could significantly improve people’s quality of life.
Today, studies are also being conducted that provide the basis for the exact demonstration of the effect of autophagy in diseases and the development of a therapeutic intervention in such cases. If one does not allow one to sit or overact the autophagic system, it contributes to the survival of its cells. Autophagy is easiest to control with lifestyle. Modest nutrient intake measured for physical activity as well as regular exercise have been shown to activate autophagy.
In connection with the Nobel Prize, Osumi Josinori's work was praised by Hungarian researchers such as
Gábor Juhász, head of the Lendület Drosophila Autophagy Research Group at the Szeged Biological Research Center of the Hungarian Academy of Sciences and Attila Kovács, teacher of the Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University.